Endocrine Abstracts

There is an accumulating amount of evidence that the metabolic adaptations to endurance exercise that result in increased intramuscular triglyceride (IMTG) stores and IMTG oxidation during exercise, also exert a protective effect on muscle insulin sensitivity. This seems to be a contradiction (known as the athlete's paradox) as large IMTG stores in sedentary and obese individuals coexist with high levels of fatty acid (FA) metabolites (specifically long-chain acylCoA, DAG and ...